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 > 【Complement Component C5a】重组蛋白信息

Complement Component C5a产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
C5A-H5116
Human
human-Complement-C5a-Protein
C5A-M51H4
Mouse
Mouse Complement Component C5a Protein, His Tag
C5A-C5118
Cynomolgus
Cynomolgus Complement Component C5a Protein, Tag Free
C5A-H525a
Human
Human Complement Component C5a Protein, Fc Tag

Complement Component C5a Molecule Synonym Name

C5a,Complement Component 5a

Complement Component C5a 分子背景

Human Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells; C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation; C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism; C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system; C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.

Complement Component C5a 参考文献

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