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 > 【CD200】重组蛋白信息

CD200信息

英文名称:OX-2 membrane glycoprotein
中文名称:OX-2膜糖蛋白
靶点别称:OX-2 membrane glycoprotein,MOX1 ,MOX2,CD200,CD_antigen=CD200
上市药物数量:0
临床药物数量:2
最高研发阶段:临床二期

CD200产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
OX2-H5228
Human
Human CD200 / OX-2 Protein, His Tag
OX2-H5251
Human
Recombinant Human CD200 / OX-2 Protein
OX2-H82F1
Human
Biotinylated Human CD200 / OX-2 Protein, Fc Tag, Avi Tag

CD200 分子别名

CD200,MOX1,MOX2,MRC,OX-2,My033

CD200 分子背景

CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

CD200 参考文献

CD200临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Samalizumab ALXN-6000 临床二期 亚力兄制药, The Leukemia & Lymphoma Society 急性骨髓性白血病 详情
AFM-24 AFM-12; AFM-18; AFM-20; AFM-21; AFM-22; AFM-24; AFM-24+; AFM-26; AFM-26+ 临床前 Affimed, Amphivena Therapeutics 结肠直肠癌, 肺癌, 急性骨髓性白血病, 头颈癌, 癌症

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