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 > 【Activin RIB】重组蛋白信息

Activin RIB产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
ACB-H5251
Human
Human ACVR1B /ALK4 Protein, With C-Fc Tag

Activin RIB 分子别名

ACVR1b,ALK4,ACVRLK4,ACTR-IB,SKR2

Activin RIB 分子背景

Activin receptor type-1B (ACVR1B) is also known as Activin receptor-like kinase 4 (ALK-4), Serine/threonine-protein kinase receptor R2 (SKR2), which belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. ACVR1B contains one GS domain and one protein kinase domain. The catalytic activity of ACVR1B is “ATP + [receptor-protein] = ADP + [receptor-protein] phosphate”. ACVR1B acts as a transducer of activin or activin like ligands (e.g., inhibin) signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on to recruit the R-SMADs SMAD2 or SMAD3. ACVR1B also transduces signals of nodal, GDF-1, and Vg1.

Activin RIB 参考文献

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