搜索
 > 【CD3 delta】重组蛋白信息

CD3 delta产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CDD-C52H8
Cynomolgus
Recombinant Cynomolgus CD3 delta / CD3D Protein
CDD-H5224
Human
Human CD3 delta Protein, His Tag

CD3 delta 分子别名

CD3D,CD3-DELTA,T3D

CD3 delta 分子背景

CD3D is also known as CD3-DELTA, T3D, and is a single-pass type I membrane protein. CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.

CD3 delta 参考文献

消息提示

请输入您的联系方式,再点击提交!

确定