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 > 【beta 2-Microglobulin】

beta 2-Microglobulin信息

英文名称:Beta-2-microglobulin
中文名称:β2微球蛋白
靶点别称:HDCMA22P,CDABP0092,B2M,Beta-2-Microglobulin,Beta Chain Of MHC Class I Molecules,Beta-2-Microglobin,IMD43,beta 2-Microglobulin
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

beta 2-Microglobulin产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
B2M-C5226
Cynomolgus / Rhesus macaque
Cynomolgus / Rhesus macaque beta 2-Microglobulin / B2M Protein, His Tag
B2M-H5225
Human
Human beta 2-Microglobulin / B2M Protein, His Tag
ACRO质量管理体系
 
评论(3)
B2M-C5226|Cynomolgus / Rhesus macaque beta 2-Microglobulin / B2M Protein, His Tag
  1. 188XXXXXXX0
  2. 0人赞
  3. 由于之前买的蛋白余量不足本次做抗体亲和力检测不太够,又回购了一支,两批次产品结果非常一致,感谢ACRO长期的陪伴
  4. >
  5. 2024-01-29
B2M-C5226|Cynomolgus / Rhesus macaque beta 2-Microglobulin / B2M Protein, His Tag
  1. 199XXXXXXX8
  2. 0人赞
  3. 本次买该蛋白主要原因流式检测噬菌体展示抗体亲和力,阳性对照结合亲和力明显,实验组也获得了高质量数据,太值得购买了!
  4. 2024-02-03
B2M-C5226|Cynomolgus / Rhesus macaque beta 2-Microglobulin / B2M Protein, His Tag
  1. 199XXXXXXX5
  2. 0人赞
  3. 本次购买Cynomolgus B2M蛋白主要用于相关抗体流式细胞检测,与阳性细胞结合位移明显,亲和力很不错,值得推荐!
  4. 2024-01-23
 

beta 2-Microglobulin 分子别名

B2M

beta 2-Microglobulin 分子背景

β2 microglobulin is also known as Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).

beta 2-Microglobulin 前沿进展

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