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IL-31信息

英文名称:Interleukin-31
中文名称:白介素31
靶点别称:Interleukin 31,IL-31
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

IL-31产品列表

ACRO质量管理体系
 
评论(3)
IL1-H5247|Human IL-31 Protein, His Tag (MALS verified)
  1. 187XXXXXXX9
  2. 1人赞
  3. 货到的还挺快的,比国外的货快多了,质量不比国外的差,最主要的价格比国外的货便宜很多,对于科研来说还是很划算的,效果杠杠的,直接上图
  4. >
  5. 2022-11-15
IL1-H5247|Human IL-31 Protein, His Tag (MALS verified)
  1. 176XXXXXXX8
  2. 0人赞
  3. 产品稳定性,活性都很好,与自己表达的蛋白做了对比,果断选择Acro的。批次间稳定性好,价格也不贵,关键非常节约时间。
  4. 2024-02-27
IL1-H5247|Human IL-31 Protein, His Tag (MALS verified)
  1. 151XXXXXXX5
  2. 0人赞
  3. 我们采购IL1-H5247主要应用于实验室大批量的Elisa实验,目的是为了获得特异性较强的单克隆,为后续实验所需
  4. 2023-10-25
 

IL-31分子别名

IL-31,IL31,Interleukin-31

IL-31分子背景

IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

IL-31临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
NM26-2198 NM-26-2198 临床一期 日本科研製薬株式会社, Numab Therapeutics Ag 炎性疾病, 特应性皮炎 详情

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