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Mouse ROR2 / NTRKR2 Protein, Fc Tag

分子别名(Synonym)

ROR2,NTRKR2

表达区间及表达系统(Source)

Mouse ROR2, Fc Tag (RO2-M5253) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Gly 403 (Accession # Q9Z138-1).

Predicted N-terminus: Glu 34

蛋白结构(Molecular Characterization)

Online(Glu 34 - Gly 403) Q9Z138-1

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 67.6 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Mouse ROR2, Fc Tag (Cat. No. RO2-M5253) SDS-PAGE gel

Mouse ROR2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

背景(Background)

Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

 

前沿进展

 
货号/价格

RO2-M5253-100ug / ¥4500

RO2-M5253-1mg (500ug X 2) / ¥25000

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ROR2靶点信息
英文全称:Tyrosine-protein kinase transmembrane receptor ROR2
中文全称:蛋白酪氨酸激酶跨膜受体ROR2
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:2详情
最高研发阶段:临床二期
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