搜索
 >  其他蛋白>Transferrin R >CD1-H5243

Human Transferrin R / CD71 Protein, His Tag

分子别名(Synonym)

CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

表达区间及表达系统(Source)

Human Transferrin R, His Tag (CD1-H5243) is expressed from human 293 cells (HEK293). It contains AA Cys 89 - Phe 760 (Accession # P02786-1).

Predicted N-terminus: His

蛋白结构(Molecular Characterization)

Online(Cys 89 - Phe 760) P02786-1

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 77.0 kDa. The protein migrates as 80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 12 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human Transferrin R, His Tag (Cat. No. CD1-H5243) SDS-PAGE gel

Human Transferrin R, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

 

活性(Bioactivity)-ELISA

Biotinylated Human ELISA

Immobilized Human Transferrin, His Tag (Cat. No. TRN-H4229) at 2 μg/mL (100 μL/well) can bind Human Transferrin R, His Tag (Cat. No. CD1-H5243) with a linear range of 1-25 ng/mL (QC tested).

Protocol

背景(Background)

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

 

前沿进展

 
货号/价格

CD1-H5243-100ug / ¥2800

CD1-H5243-1mg / ¥17000

开发建议
文档
联系电话:
400-682-2521(全国)
010-57737274(北京)
021-26136428(上海)
运输方式
订单邮箱:
order.cn@acrobiosystems.com
技术支持邮箱:
techsupport@acrobiosystems.com
Transferrin R靶点信息
英文全称:Transferrin receptor protein 1
中文全称:转铁蛋白受体
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:3详情
最高研发阶段:临床二期
查看更多信息

消息提示

请输入您的联系方式,再点击提交!

确定