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Human Serpin A3 Protein, His Tag

分子别名(Synonym)

SERPINA3,ACT,AACT,GIG24,GIG25

表达区间及表达系统(Source)

Human Serpin A3, His Tag (SE3-H5221) is expressed from human 293 cells (HEK293). It contains AA His 24 - Ala 423 (Accession # AAH03559).

Predicted N-terminus: His 24

蛋白结构(Molecular Characterization)

Online(His 24 - Ala 423) AAH03559

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 46.6 kDa. The protein migrates as 50-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human Serpin A3, His Tag (Cat. No. SE3-H5221) SDS-PAGE gel

Human Serpin A3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

背景(Background)

Serpin A3 is also known as Alpha-1-antichymotrypsin (ACT or AACT), Cell growth-inhibiting gene 24/25 protein, which belongs to the serpin family. Serpin A3 can bind DNA. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

 

前沿进展

 
货号/价格

SE3-H5221-50ug / ¥3150

SE3-H5221-1mg / ¥22000

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