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Human LYPD3 / C4.4A Protein, His Tag

分子别名(Synonym)

LYPD3,MIG-C4,C4.4A

表达区间及表达系统(Source)

Human LYPD3, His Tag (LY3-H52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 31 - His 286 (Accession # AAH39167).

Predicted N-terminus: Leu 31

蛋白结构(Molecular Characterization)

Online(Leu 31 - His 286) AAH39167

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 28.7 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human LYPD3, His Tag (Cat. No. LY3-H52H5) SDS-PAGE gel

Human LYPD3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

背景(Background)

Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 ,C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein,which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.

 

前沿进展

 
货号/价格

LY3-H52H5-100ug / ¥2600

LY3-H52H5-1mg (500ug X 2) / ¥16000

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LYPD3靶点信息
英文全称:Ly6/PLAUR domain-containing protein 3
中文全称:LY6/PLAUR结构域蛋白-3
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:1详情
最高研发阶段:临床一期
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