搜索
 >  其他蛋白>FKBP4 >FK4-H52Q3

Human FKBP4 / FKBP52 Protein, His,PA Tag

分子别名(Synonym)

FKBP4,FKBP52

表达区间及表达系统(Source)

Human FKBP4, His,PA Tag (FK4-H52Q3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 459 (Accession # AAH01786).

Predicted N-terminus: Met 1

蛋白结构(Molecular Characterization)

Online(Met 1  - Ala 459) AAH01786

This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human FKBP4, His,PA Tag (Cat. No. FK4-H52Q3) SDS-PAGE gel

Human FKBP4, His,PA Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

背景(Background)

Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.

 

前沿进展

 
货号/价格

FK4-H52Q3-50ug / ¥3800

FK4-H52Q3-500ug (100ug X 5) / ¥19800

开发建议
文档
联系电话:
400-682-2521(全国)
010-57737274(北京)
021-26136428(上海)
运输方式
订单邮箱:
order.cn@acrobiosystems.com
技术支持邮箱:
techsupport@acrobiosystems.com

消息提示

请输入您的联系方式,再点击提交!

确定