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Human CD37 Protein, Fc Tag

分子别名(Synonym)

CD37,Tspan-26,TSPAN26

表达区间及表达系统(Source)

Human CD37, Fc Tag (CD7-H526x) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Asn 240 (Accession # AAI06753).

蛋白结构(Molecular Characterization)

Online(Ala 113 - Asn 240) AAI06753

This protein carries a human IgG1 Fc tag at the N-terminus.

The protein has a calculated MW of 41.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>90% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human CD37, Fc Tag (Cat. No. CD7-H526x) SDS-PAGE gel

Human CD37, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

背景(Background)

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

 

前沿进展

 
货号/价格

CD7-H526x-50ug / ¥3150

CD7-H526x-1mg (500ug X 2) / ¥19800

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CD37靶点信息
英文全称:Leukocyte antigen CD37
中文全称:白细胞抗原CD37
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:8详情
最高研发阶段:临床二期
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