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Human APCS / SAP / PTX2 Protein, His Tag

分子别名(Synonym)

PTX2,APCS,SAMP,SAP,Pentraxin 2

表达区间及表达系统(Source)

Human APCS, His Tag (APS-H5229) is expressed from human 293 cells (HEK293). It contains AA His 20 - Val 223 (Accession # P02743-1).

Predicted N-terminus: His 20

蛋白结构(Molecular Characterization)

Online(His 20 - Val 223) P02743-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 24.1 kDa. The protein migrates as 26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human APCS, His Tag (Cat. No. APS-H5229) SDS-PAGE gel

Human APCS, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

背景(Background)

Serum amyloid P-component (SAP) is also known as Pentraxin 2 (PTX2), APCS, which belongs to the pentaxin family. SAP contains one pentaxin domain. PTX2 is a secreted homopentamer protein which is found in serum and urine. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. SAP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. SAP may also function as a calcium-dependent lectin. SAP has certain sequence homology with C-reactive protein (CRP).

 

前沿进展

 
货号/价格

APS-H5229-100ug / ¥2500

APS-H5229-1mg (500ug X 2) / ¥15000

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APCS靶点信息
英文全称:Serum amyloid P-component
中文全称:血清淀粉样蛋白P组分
种类:Homo sapiens
上市药物数量:0详情
临床药物数量:4详情
最高研发阶段:临床二期
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