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Human Galectin-3 Protein, His Tag

分子别名(Synonym)

Galectin-3,LGALS3,MAC2,Gal-3,35 kDa lectin,CBP 35,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen

表达区间及表达系统(Source)

Human Galectin-3, His Tag (GA3-H5247) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 250 (Accession # P17931-1).

Predicted N-terminus: His

蛋白结构(Molecular Characterization)

Online(Met 1 - Ile 250) P17931-1

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 27.5 kDa. The protein migrates as 35-41 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

内毒素(Endotoxin)

Less than 1.0 EU per μg by the LAL method.

纯度(Purity)

>95% as determined by SDS-PAGE.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in 50 mM HEPES, 150 mM NaCl, 5 mM EDTA, 2 mM TCEP, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法(Reconstitution)

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

电泳(SDS-PAGE)

Human Galectin-3, His Tag (Cat. No. GA3-H5247) SDS-PAGE gel

Human Galectin-3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

背景(Background)

Galectin-3 (Gal-3) is also known as LGALS3, 35 kDa lectin, Carbohydrate-binding protein 35 (CBP 35), Galactose-specific lectin 3, Galactoside-binding protein (GALBP), IgE-binding protein, Laminin-binding protein, Mac-2 antigen, Lectin L-29. Galectin-3 is a member of the lectin family. LGALS3 / Galectin-3 is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. LGALS3 / Galectin-3 has been shown to be involved in the following biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cell cycle, and apoptosis.

 

前沿进展

 
货号/价格

GA3-H5247-100ug / ¥2900

GA3-H5247-1mg (500ug X 2) / ¥18000

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Galectin-3靶点信息
英文全称:Galectin-3
中文全称:半乳糖凝集素3
种类:Homo sapiens
上市药物数量:1详情
临床药物数量:6详情
最高研发阶段:批准上市
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