SARS-CoV-2抑制剂筛选试剂盒可用于高效筛选SARS-CoV-2小分子和多肽抑制剂、以及中和抗体，能够帮助客户快速筛选和验证药物，可以有效提高研发效率。
Fig.1 Inhibition of Human ACE2 [Biotinylated]: SARS-CoV-2 S protein RBD Binding by SARS-CoV-2 inhibitor.
Serial dilutions of SARS-CoV-2 inhibitor (Cat. No. AC2-NA005) (1:2 serial dilutions, from 20 μg/mL to 0.039 μg/mL (180 nM to 0.35 nM)) was added into Biotinylated ACE2: SARS-CoV-2 S protein RBD binding reactions. The assay was performed according to the above described protocol. Background was subtracted from data points prior to log transformation and curve fitting.
* 该试剂盒可提供配套Buffer套装（Cat.No. EBS-001 ELISA Buffer Set-96T）
ACROBiosystems开发了一系列抗体滴度检测试剂盒，包括IgG抗体滴度检测试剂盒、IgM抗体滴度试剂盒、总抗体滴度检测试剂盒、总保护性中和抗体滴度检测试剂盒等。该系列抗体滴度检测试剂盒可应用于疫苗研发领域，通过检测抗体含量验证疫苗的有效性，还可用于评估感染病人体内抗体滴度的科学研究。中和抗体的滴度检测结果体现其病毒中和能力，可作为筛选药物的依据之一。
Fig.2 Detection of Monoclonal Anti-SARS-CoV-2 Antibody, Human IgG1 titer by Indirect-ELISA Assay
Immobilized SARS-CoV-2 S protein RBD at 0.2 μg/mL (100 μL/well) can bind Monoclonal Anti-SARS-CoV-2 Antibody, Human IgG1 in 1:50 human serum.Detection was performed using HRP-Conjugated Anti-human IgG antibody with sensitivity of 24 ng/mL.
Fig.3 Determination of Anti-SARS-CoV-2 Neutralizing Antibody titer in different concentrations of human serum.
Neutralizing titer of Anti-SARS-CoV-2 Neutralizing Antibody, Human IgG1 (Cat.No.SAD-S35) measured by Anti-SARS-CoV-2 neutralizing antibody titer serologic assay kit (Cat. No. TAS-K003) in different concentrations of human serum (CV < 30%).
利用双抗体夹心法检测SARS-CoV-2抗原蛋白，灵敏度高，可通过检测抗原蛋白确定病毒感染情况、指导进行疫苗开发设计。
ACROBiosystems研发了SARS-CoV-2 S1抗原蛋白和N抗原蛋白检测试剂盒，产品即将上线，敬请期待。
预包被S1蛋白和RBD蛋白的酶标板，可用于快速定量抗SARS-CoV-2抗体或ACE2蛋白。该系列产品灵敏度高、重现性好、可自动化高通量，适用于中和抗体筛选、生物淘选、ELISA检测等场景，有助于提高病毒治疗药物、疫苗研发的效率。
Fig.4 Binding with Anti-SARS-CoV-2 S1 antibody
Immobilized biotinylated SARS-CoV2 Spike protein RBD at 1 μg/mL (100 μL/well) on Streptavidin Coated Plates, Clear, 96-Well (Cat. No. SP-11), can bind anti-SARS-CoV-2 S1 antibody with a linear range of 0.1-2 ng/mL
| Molecule | Cat. No. | Product Description |
|---|---|---|
| S protein RBD | EP-105 | SARS-CoV-2 Inhibitor Screening Kit |
| S1 protein | TAS-K001 | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (Spike protein S1) |
| S protein RBD | TAS-K002 | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (Spike protein RBD) |
| TAS-K003 | Anti-SARS-CoV-2 Neutralizing Antibody Titer Serologic Assay kit | |
| S protein | TAS-K007 | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (S protein trimer) |
| Nucleocapsid protein | TAS-K008 | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (Nucleocapsid Protein) |
| S1 protein | SP-12 | SARS-CoV-2 Spike S1 protein-Coated Plates, Clear, 96-Well |
| S protein RBD | RP-13 | SARS-CoV-2 Spike protein RBD-Coated Plates, Clear, 96-Well |
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